Monday, September 30, 2019

Lims

LIMS In the typical scientific laboratory there is a large amount of data that must be tracked and analysed. In my current work setting we collect data from outside laboratories, analyse the data, and then return the data. We process thousands of samples per week. This makes tracking and sorting the data very cumbersome. We basically serve as a clearinghouse for data to be batched out to our customers, the independent researcher. Our laboratory considers itself a high-throughput sequencing centre. Our daily objective is to make the lab more automated. We are continually striving to use more robots or automated data entry.For automated data entry we use bar codes. Bar coding tends to have fewer errors in data entry. It also allows us to generate a greater amount of information for any given sample. The more we can automate the process the more samples we are able to put through the system. Each of the independent researchers in the company is looking for a particular disease by identi fying the disease-causing gene. Once the gene has been located the researcher must get the DNA sequence from the gene. That is our job. We at the sequencing centre take the DNA sample, with the gene, and run the sample on our automated machines.Once the sample has been analysed we put the analysed sample, also known as the DNA sequence, into a database that the researcher can access. This is a very general idea of what the Sequencing Centre does. The role of the Laboratory Information Management System (LIMS) is to keep track of this data. The accuracy of the LIMS is crucial for an efficient and effective workflow. The analysed sample must be coordinated with the correct sample name that the researcher gives to the Sequencing Centre. This means that everything must be entered into the database correctly. The data must also exist in a safe and accessible database.The data flow can be characterized in the following context diagram. We have just begun the implementation of a new LIMS s ystem. Hopefully this analysis will help to guide our laboratory as we move towards its implementation. LIMS Functionality Different LIMS systems offer a variety of functionality. The systems have developed from simple data entry and record storage to complex relational database driven tools. They now offer enhanced functionality often provided over the wireless networks and company intranet, allowing greater flexibility for inspections in remote and difficult environments Regulations and ComplianceThe functionality of the LIMS system is far greater than just tracking and reporting on samples. LIMS systems must often comply with regulations that affect the user, for example a manufacturer of pharmaceuticals is obliged to operate under the cGMP 21 CFR Part 210 – Current Good Manufacturing Practice in Manufacturing, Processing, Packing, or Holding of Drugs. Other regulations that LIMS systems must operate under include HIPAA, ISO 9001, and ISO 15189. It is important for systems to have the ability to accept e-signatures, as well as offer audit trails and chain of custody.These types of functionality are required to ensure that the correct persons have access to the sample and the results of the sample inspection Equipment Calibration and Maintenance When inspections are carried out the equipment used to extract the sample and to test the sample must be maintained correctly and calibrated so that there are no errors introduced into the test results. The LIMS system should contain maintenance records of the equipment used in testing so that notifications can be generated to perform regular preventive maintenance.With some instruments and equipment, the requirement may include calibration after a certain number of uses, for example the use of a depth micrometre may require that it is calibrated after 50 uses or every month, whichever comes first. LIMS systems can also contain the calibration instructions so that a notification and a calibration instruction s heet can be sent to the maintenance department or a specialty outside vendor. LIMS Expansion Pre-1982 Laboratory notebooks and handwritten reports/charts were used to track and report information.In-house information systems were configured by a few laboratories. Custom-built LIMS became available from third-party vendors. 1982 The first commercial LIMS, known as first generation (1G) LIMS, are introduced. These 1G LIMS placed laboratory functions onto a single minicomputer, providing greater lab productivity and functionality as well as the first automated reporting capabilities. 1988 Second generation (2G) LIMS become available. 2G LIMS used the available market technology of third-party commercial relational databases (RDB) to provide application-specific solutions.Most 2G LIMS relied on minicomputers, but PC-based solutions were beginning to emerge. 1991 The move toward open systems ushered in third generation (3G) LIMS, which combined the PC's easy to use interface and standard ized desktop tools with the power and security of minicomputer servers in a client/server configuration. 1995 Fourth generation (4G) LIMS decentralize the architecture further. Processing can be performed anywhere on the network. Thus, all clients and servers can operate in either capacity depending upon the data load at any particular instance Pros and ConsMost LIMS products allow the laboratory to; register work requests; print analytical worksheets; monitor and communicate sample/technique backlogs; schedule work; acquire and store analytical data; monitor the quality of all analytical work; approve analytical data for client release; print and store analytical reports and invoices; protect the security of all data; track and locate samples in storage; track and communicate all quality control in the laboratory; provide laboratory management with production and financial statistics and with client information, e. . , names, addresses, sales figures, etc. An appropriately designed and installed LIMS can quickly bring accuracy and accessibility to the flow of samples and data in any laboratory. The real value of a LIMS is the ability to maximize sample throughput and minimize labour costs. Laboratory throughput is improved in a number of different ways. The most obvious gain in productivity occurs through the elimination of data entry via on-line instruments. Also, there will be a significant decrease in data entry errors.Finally, the up-to-date sample in-flow data available from a typical LIMS allows laboratory supervisors and bench personnel to better schedule analytical work, minimize â€Å"downtime† and maximize batch size. Some other effects are that there are better visible quality control checks and centralized data. The ability to monitor, track and communicate data and quality control information gives the laboratory the tools to improve methods and work practices. The end result is that people in the lab able to process more samples per hour worked. The problems Rushed or Incomplete InstallationLIMS installation can be expensive. As a result laboratory management has a tendency to reduce costs by shortening the time spent on-site by the design team. In addition, several installation phases may be required in order to allow laboratory personnel time to learn and apply each LIMS feature before adding the next. Effective communication between the bench personnel and the design team is key to ensuring a successful project. The best way to facilitate this communication is by extending and phasing the installation. Lack of Technician Access to the LIMSA problem that arises in some organizations as laboratory and support staff begin to use the system is a failure to recognize and remove access bottlenecks. For a LIMS to function smoothly all personnel must have their own access point. Access expansion can usually be spread over six to eighteen months as the laboratory assimilates the LIMS and usage increases. Design/Scoping Pr ocedure The design/scoping stage prior to acquiring our LIMS has involved the review and analysis of available software/hardware packages as well as the definition and documentation of our laboratory’s requirements.The error here is could be that bench personnel are excluded from the process. To resolve this problem we have had frequent meetings with the personnel in our lab. Some laboratories might go into a LIMS program believing that future requirements for bench level supervision will be reduced or eliminated. It has been recognized by many that LIMS is simply a tool and as such cannot manage the laboratory or take the place of personnel supervision. A LIMS will effectively provide current, reliable and complete operational data.The easy access to accurate data allows management to significantly enhance the quality and speed of decision making. Decision making becomes based more on fact rather than instincts. Many LIMS products tend to function more like accounting or fin ancial databases. This could be related to the educational and work experience of most software professionals. The demand for financial and accounting database packages means that the software industry is more familiar with this type of requirement than with a highly technical application like a LIMS.Thus, the average software professional does not usually have the background to effectively interpret a laboratory’s requirements. This communication problem can manifest itself in LIMS systems that do not easily fit into laboratory operations. Often the laboratory must significantly alter procedures and work flow in order to conform to the LIMS. This requirement for wholesale change significantly complicates LIMS installations and it might have poor acceptance and commitment support personnel to the project. A similar problem often occurs in large organizations with dedicated Information System (IS), departments.Significant conflict and problems can arise when IS personnel recom mend the most up-to-date hardware or software architecture regardless of the functionality, fit or overall cost to the laboratory. The end result of this process is that the laboratory must undergo significant change in order to conform to the product purchased. In the extreme case laboratories can wind-up having to increase overhead, e. g. , more data handling, in order to use LIMS systems that have been designed not for the laboratory but for the accounting or production departments.The keys to success are flexibility, adaptability, ease of evolution and support, and most importantly overall system speed. The speed issue is very critical as bench personnel will not use something that is slow or awkward. If the system saves bench personnel time they will quickly â€Å"buy into† the project and aggressively move the process forward. The key in any LIMS development should be to achieve a majority of the desired functionality without compromising system speed. Most laboratories need time to assimilate a LIMS before being able to take full advantage of all of its features.As a result of this ‘break-in period’ the more complex features can usually be postponed a year or two without affecting the success of the program. [17] This implementation delay may also allow laboratory personnel the chance to provide more input into the critical final stages of system optimization. Installation Stage The goal of any LIMS installation must be to acquire a system that will make the jobs of bench personnel easier and thus increase the efficiency of the organization. In order to be successful, the LIMS system must be accepted and welcomed by the bench personnel.Often the first contact front-line personnel have with the new system is during installation, long after all decisions have been made. This situation often leads to significant software and LIMS configuration problems that require major software re-writes, hardware retro-fits and/or disruptive organiza tional changes. In addition, analytical and support staff are more likely to resist the new system if they have had little input into its design and operational characteristics. The installation phase of a LIMS program is critical to the overall success of the project.It is during LIMS installation that personnel must be taught how to use the product and where the software designers get their first view of how the LIMS will fit into and function in the laboratory. The installation phase of a LIMS project can take from weeks to months depending on the size of the laboratory and the complexity of the project. No Staff Training Bench personnel must be taught how to use the LIMS. As with any subject laboratory staff must be taught progressively so that personnel have a chance to use and apply what they learn.In laboratories where the LIMS training has been available and sustained the staff will be using the LIMS at a similar level. This consistency of approach builds team work and staff efficiency increases. In laboratories where training has not been a priority, staff will be using the LIMS at different levels. This situation can create a great deal of competition in the laboratory as turf wars erupt over the adoption of new or unused LIMS features. Poorly trained staff fears the new features and as a result delay or resist their implementation.Poor Feedback Mechanism As noted above communication is a key component of any successful LIMS project. It is important that laboratories make sure that a well-developed feedback mechanism is put in place during the installation of a LIMS so that laboratory personnel can bring forward problems and see quick resolution. Staff often hesitate to bring forward complaints and will instead work around the problem. One successful approach that has been used by organizations to solve this problem has been regular procedural audits.The process required to perform an audit usually brings to light LIMS defects or problems that staff have been coping with. This is has already been implemented for other laboratory procedures in our lab. Conclusion Companies require that quality is part of every link in the supply chain, whether it is raw material at a vendor’s facility or finished goods delivered to a customer. To ensure that the quality personnel are able to achieve the optimum results, a Laboratory Information Management System is vital to that success.

Sunday, September 29, 2019

Cheat Sheet Finance Essay

One year ago, you purchased 1,200 shares of Berry, Mayell, and Wheeler (BMW) stock for $21.20 per share. You have received dividend payments equal to $0.60 per share. Today, you sold all of your shares for $22.20 per share. What is your total return (dollar and percent) on this investment? (4 points) [pic] Castella, Norwood, and Ngoc (CNN) stock had returns of 8%, -2%, 4%, and 16% over the past four years. What are the mean and standard deviation of this stock for the past four years? (6 points) The long term inflation rate average was 3.2% and you invested in long term corporate bonds over the same period which earned 6.1%. What was the average risk premium you earned? (3 points)[pic] Use the following information to answer questions 11 and 12. You purchased one of Fan, Igli, Sherrill, Harper, Evans, and Rashid (FISHER) Corp’s 8% coupon bonds one year ago for $1,028.50. These bonds make annual payments and mature six years for now. Suppose you decide to sell your bond today, when the required return on the bond is 7%. The inflation rate was 4.8% over the past year. What would be your total (i.e., nominal) rate of return on the investment? (7 points) To find the return on the coupon bond, you first need to find the price today. The bond now has six years to maturity, so the price today is: [pic] You received the coupon payments on the bond, so the nominal return was: [pic] What would be your real rate of return on the investment? (4 points) And using the Fisher equation to find the real return, we get [pic] Return and Risk: Statistics and CAPM (various points each) If the covariance of Caroline and Oberkrom (CO) Inc. stock with Van, Aleksandra, and Richter (VAR) Co. stock is0.0065, then what is the covariance of VAR Co. stock with CO Inc. stock? (3 points) Answer: -0.0065 Suppose the risk-free rate is 6.3% and the market risk premium is 8.5%. The market portfolio has a variance of 0.0498. Blagg, Elizabeth, Tendler, and April (BETA) Portfolio has a correlation coefficient with the market of 0.45 and a variance of 0.1783. According to the CAPM, what is the expected return on BETA Portfolio? (8 points) First, you need to find the standard deviation of the market and the portfolio, which are: [pic] [pic] Now, you can use the equation for beta to find the beta of the portfolio, which is:[pic]; or [pic] [pic] [pic] Assume that you are interested in acquiring the exclusive rights to market a new product. You estimate that it will cost you $500 million upfront. You also believe that the product will generate an NPV of -$165. You expect to operate without serious competition for the next five years. Use the following inputs to the Black-Scholes options pricing model: S, the current PV of the project’s E(CFs): $335 million ÏÆ'2, the variance of the project’s E(CFs):0.422 = 0.1764 X, the initial investment in the project:$500 million T, the period of exclusive rights to the project:5 years t, the number of years delayed:1 – 5 years rf, the 5-year risk-free rate:5% DY, the cost to delay [pic]:0.20

Saturday, September 28, 2019

Summary (maple syrup) Essay Example | Topics and Well Written Essays - 500 words

Summary (maple syrup) - Essay Example The remaining 82% of the world’s Maple syrup is produced in Canada (Pure Canada Maple, 2013). An interesting fact it is little known about true Maple syrup is the fact that it is 100% pure and natural. Furthermore, strict guidelines are in place with regards to the production of Maple syrup to which both the United States and Canada subscribe. One of these professional organizations that helps to monitor the production of Maple syrup in Canada is known as the Federation of Quebec Maple Syrup Producers. In order to ensure that the raw material that is utilized to make maple syrup, the tree itself, remains healthy, each year trees are At different places and varying heights so that growth, re-growth, and healing can take place in between the seasons of harvest. Moreover, an added benefit of Maple syrup is with respect to the fact that it represents an alternative to traditional sugar. As such, baked goods, glazes, and sweets can all be flavored with Maple syrup rather than sugar itself. Maple syrup production itself is a massive business within Canada and the United States. For instance, within Canada alone 8600 Maple syrup businesses are known to exist and registered with the government; a full 7400 of these exist in Quà ©bec itself. However, even though Maple for syrup production dominates the Canadian market in the current era, it was in fact the Amerindians who taught Canadians how to tap and boil sap in order to make maple syrup in the first place. As a function of this level of knowledge, Canadians have been known to extract around 67.6 million pounds of syrup each and every year; exporting this to over 50 different countries around the world (Wild Blueberries, 2012). The trees that Maple syrup itself is harvested from typically live around 30 years; moreover, the base of the tree must be at least 12 inches in diameter prior to being tapped. Further, only 10

Friday, September 27, 2019

The Notebook Research Paper Example | Topics and Well Written Essays - 750 words

The Notebook - Research Paper Example This particular scene, â€Å"It’s Not Over,† appears in the second half of the film and again is on the water, a realistic setting. The couple, Noah and Allie, has been separated for seven years, but now they are reunited and spend an emotional weekend reacquainting themselves with the reasons they fell in love years ago and discovering the twists in events that have kept them apart. The water is not red this time, nor is the water calm, but choppy and the wind blows through young Allie’s hair. It begins to rain and she tries to protect herself with a dish towel, which clearly isn’t going to help as the rain becomes a torrent. Noah laughs at her flimsy attempt to protect herself from the downpour. As in the opening scene of the film, in â€Å"It’s Not Over,† there are the elements of a rowboat and a lake. In the opening scene, however, the waters are peaceful, suggesting a calm situation, for now. The general coloring of the film’s opening scene is in red tones, suggesting that the calm and peace is not meant to last, but that the characters will experience turbulence at some point. In the film’s opening, the adult Noah, played by James Garner, is rowing the boat on the red, but calm waters. The red color cast on the water is also used later in some of the clothing worn by Allie. As the film unfolds, we learn that the color red is symbolic of Allie’s very passionate nature which strongly impacts their relationship. The reunited lovers are happy on the water, but as the storm ensues and they reach the dock, unexpressed emotions gush forth and Allie asks Noah why he never wrote to her. The sky is dark and windy, and the lovers becoming soaked. The weather’s elements all invoke the emotional climax of the scene. We see in the scene’s tranquil beginning, the lovers in their boat. It is across the lake from the camera, a widescreen shot showing the characters in

Thursday, September 26, 2019

Uncertainty Reduction Theory Critique Assignment

Uncertainty Reduction Theory Critique - Assignment Example However, I have come to realize that this is only the short term goal. The long-term goal of the entire process is to gain some related benefits. Having said that, I think maximizing relational outcomes is the ideal motivator when people encounter new people. The majority of human beings are motivated into gaining more information about other people simply because of maximizing on the relational outcomes. It is because almost all people tend to be less interested in others that have little significance to their lives. For example, an average or poor performing academic student will tend to gain information about another top performing student not for reducing uncertainty, but for gaining academic related benefits. In another example, a political candidate will choose a running mate, not because good friendship, but because of amassing more votes that would eventually help the pair at winning the elections. Due to our current life situation, we approach new people to fulfill an emotional, psychological or physiological need. Basing on the same concept, our group picked on the primary motivator in class because we want to maximize on the relational outcome. We made that choice because we want someone that is more like a role model and one that will help us through our emotional, psychological and physiological needs. Making such choice makes more sense than uncertainty reduction theory in that learning and understanding a person does not entirely add value to another person’s life. Therefore, it is justified to conclude that people are motivated by rewards or associated benefits they would gain from a new person they

Wednesday, September 25, 2019

The Bill of Rights and Later Amendments Essay Example | Topics and Well Written Essays - 1250 words

The Bill of Rights and Later Amendments - Essay Example Due to the continuing reluctance of the Southern states in abolishing slavery, the federal government had found justification in going against state’s rights us protected by the Tenth Amendment by introducing the Fourteenth Amendment and establishing further federal authority to protect human rights. (Brown v. Board of Education of Topeka, Kansas [1954]. The right to vote by each citizen is not based on federal constitutional right but based on state’s right as protected by the Tenth Amendment and further explained in the Latin maxim Expressio unius est exclusio alterius (the express mention of one thing excludes all others) that applies to the federal governments powers (Calabresi and Prakash 1994). The powers of the federal government are limited to what is provided by the Constitution and all other powers are hence given to the state, giving them more independence and local autonomy. As an old rule, the federal government cpuld not interfere with state acts and must keep its interaction in arms length, avoiding any form of violation of each state’s rights. ... Furthermore, aside from the Equal protection clause that is also provided in the Fourteenth Amendment, the federal constitution does not guaranty political representation or right to vote. It was held in Alexander v. Daley (2000) that "The Equal Protection Clause does not protect the right of all citizens to vote, but rather the right of all qualified citizens to vote". Qualification to vote depends on state laws and so is the right to vote. The interpretation of the Tenth Amendment provides that it is the state who has the authority to provide for the voting rights of its citizens. The Constitution again has given respect to local state’s independence and autonomy. In the case of Bush v. Gore (2000), Chief Justice William Rehnquist and Associate Justice Antonin Scalia provided that "the individual citizen has no federal constitutional right to vote for electors for the President of the United States.". It is the state legislature who has vested power to choose presidential el ectors, the right is rooted from the Constitution that provides that â€Å"Each State shall appoint, in such manner as the Legislature therefore may direct, a number of Electors†¦Ã¢â‚¬  (Article II,  § 1, cl. 2). Individual citizens participate in the Presidential elections by voting a representative of their state (elector), who in turn would vote for the nominated and pledged candidate by the given state. State election is won by plurality of votes in each state as they chose for a senator or state representative that will represent them in Congress and in the Presidential elections (Patterson 8). A candidate must obtain an absolute majority in the Electoral College that is followed by most states except Maine and Nebraska whose votes are in proportion to the popular

Tuesday, September 24, 2019

Earth Science Essay Example | Topics and Well Written Essays - 250 words

Earth Science - Essay Example Catastrophism ultimately takes a ratchet approach and explains off much of the current formation of our geologic world through a series of sudden events which shaped our modern world. According to James (2001) the origins of this theory are largely based on the writings of Immanuel Velikovsky who postulated that many ancient myths could ultimately be attributed to a near collision between Venus and Earth. Whilst this represents a pseudo-science approach it could be further argued that Catastrophism does not have any universal guiding principles and catastrophist theories can run a wide range from impact events shaping our current biological makeup right through to the theories of Velikovsky. In terms of estimating the age of the earth, effectively people who subscribe to Catastrophism theories believe that much of the Earths development came in cycles and if one can trace back all of these cycles back to their origin they they can estimate the age of the earth (Though estimates vary widely). In contrast to Catastrophism is Uniformitarianism which postulates that most of the natural laws of science that play on our earth now, also applied since its origins. Meaning that the development of the earth has been a slow and gradual process, which is often compared to the erosion. In terms of the age of the earth, estimations can vary widely insofar as again there is no commonly universally held principles earth development. According to Tarbuck and Lutgens (2011) it is the case that both principles are not to be taken literally however it is the case that Uniformitarianism is more widely accepted amongst the geologic community today. James, B (2001) Catastrophist Theories of Life Gaining Ground It Came From Outer Space.. The New York Times [online] Available at http://www.nytimes.com/2001/08/23/style/23iht-sncat_ed3_.html Accessed on August 25th

Monday, September 23, 2019

Consciousness Essay Example | Topics and Well Written Essays - 1250 words

Consciousness - Essay Example This is disturbing only if we assume that states of consciousness are mutually exclusive. Insofar as the same subject can experience different forms of consciousness (dreams and waking reality) they need not be mutually exclusive; rather, the fear is that a totally different worldview, and therefore a totally different mode of operating in the world, may be appropriate. For example, it would be unsettling if someone managed to convince us that feudalism is the correct worldview and therefore the correct modus operandi. Our defence of the current worldview (industrial capitalism) would be motivated not only by apprehensions of the alteration in our individual condition (from factory-owner to serf) but perhaps even more by our belief in the props (e.g. belief in free speech and free enterprise) of the current worldview. Our values and beliefs are ultimately determined by our social existence; our knowledge of the world is based on our social relations and conditions. The thesis he posited in contradistinction to Rene Descartes' "Cogito ergo sum" and which is central to Karl Marx's body of work is that "It is not the consciousness of men that determines their existence, but their social existence that determines their consciousness" (Critique of Political Economy 2). Existence itself does not depend on consciousness, much less on meta- consciousness; neither does life or productivity depend on consciousness. Rather, given a certain social structure and an individual's relations to it, subjective consciousness arises from physical reality. Physical reality encompasses everyday material activity (Burke 3), which is determined by the configuration of the individual or socioeconomic class in the current relations of production. An early 21st century American farmer's consciousness arises from the sum of all the activities and relationships he enters as a farmer (planting with a seed-drill, selling his grain to a corporate miller, buying seeds from a transnational biotechnology giant); it is different from the consciousness of the miller or the biotech company, and also from that of a farmer in Soviet Russia. It is different and unique not only because of his position in a salient mode of production (industrial capitalism versus socialism), but also, and equally importantly, because of the non-economic institutions that reflect and propagate that mode of production. Thus the early 21st century American farmer's consciousness is determined also by the media, the church, the system of education, the family - in short, by all that can be summed up as 'culture.' Althusser calls these cultural institutions the Ideological State Apparatuses (ISAs) - in contrast to the Repressive State Apparatuses (Althusser 3) which operate by direct force (law, police, army). The ISAs grow up on the base of the mode of production, reflect it, and reinforce it; they represent the ideology of the dominant mode of production. This is true of every human society under every mode or production: it can be understood, not as a conspiracy (Burke 4), but as reflections in ideology of the mode of production. By reflecting the mode of production, ideology also propagates it: every time the status quo is mirrored in culture (e.g. in advertisements or

Sunday, September 22, 2019

Dworkin and legal positivists seek to provide guidelines for impartial Essay

Dworkin and legal positivists seek to provide guidelines for impartial judicial decision making, but do so in different ways and with different results. Discu - Essay Example non-Dworkian sense implies that the legal validity of a given norm, and hence whether it forms part of the law of that system, depends on its sources, not its merits. This paper discusses the jurisprudential basis of impartiality in judicial decision-making based on the theory of Dworkin and juxtaposing the same with another contemporaneous legal positivist, Professor H.L.A Hart. Dworkin, in his paper ‘The Model of Rules’, identifies and attributes to Hart a four-fold doctrine:2 (1) that law consists of ‘rules’ (understood as legal standards that differ from what Dworkin calls ‘principles’); (2) that legal rules are identified via a ‘rule of recognition’; (3) that where a rule does not control a case, judges have discretion; and (4) that in those cases where judges have discretion, neither party has a pre-existing legal right to prevail. Dworkin rejects the merit of all these four doctrines, but for the purposes of the present essay we shall limit our discussion to the last two of these four doctrines identified by Dworkin. The purpose of this essay in so far as it attempts to juxtapose Dworkin’s theory with Hart’s, shall be better served if prefaced by a brief survey of how Hart perceived the impact of judicial discretion on law-making. The variance in the two approach is best illustrated by taking as an example the ‘hard cases’ to be decided by a court of law- that is, cases which have a uniquely singular problem which has not be covered by the text of the relevant statute or which it is abundantly clear has never come within the contemplation of the legislature. Hart has consistently taken the view that, as a conceptual matter, what constitutes a question of law as ‘hard’ is that the pre-existing law is substantively indeterminate with respect to that question and is insufficient to determine a uniquely correct answer.3 Hard cases, therefore, arise because there is a gap or vacuum in the coverage of pre-existing law. Since, in such

Saturday, September 21, 2019

Explore how chapter 56 in Pride and Prejudice fits into the overall scheme of the text Essay Example for Free

Explore how chapter 56 in Pride and Prejudice fits into the overall scheme of the text Essay What social comments do you think Jane Austen is making in this chapter? Pride and Prejudice was written by Jane Austen in 1813. The novel describes and exaggerates the life in which in Austen lived. The title Pride and Prejudice refers to the ways in which Elizabeth Bennet and Mr. Darcy first view each other. The story involves the lives of many different classes and how they interact with each other; it is also informing us of the way certain types of people were treated in those days. Near the end of the novel, Lady Catherine de Burgh comes to visit Elizabeth to try and persuade her not to marry Darcy. I will explore this chapter to find out what social comments Austen tries to make throughout the novel about the world she lived in. Chapter 56 is a summary of the whole novel. Lady Catherine has come to see Elizabeth to make her withdraw her acceptance of marriage to her nephew, Mr. Darcy. Lizzy is shocked by these accusations, as she has heard nothing of the sort, so wonders where Lady Catherine heard the rumours. She is the type of person who thinks that everybodys business is her own because she is of the higher class. It has been planned since Darcy and Lady Catherines daughter were born that they were to be wed and now she hears of Darcy proposing to another lady has outraged her. That is why she has come to visit Elizabeth to stop her marrying Darcy. From the moment lady Catherine arrived she was very rude and not welcoming. She says things such as, you have a very small park here, and this must be a most inconvenient sitting room. As soon as she entered the Bennets home she made no effort on being civil or polite to their family. If Elizabeth were to behave in this manner when she was at Rosings it wouldnt have been tolerated in the slightest. The only reason Lady Catherine gets away with it is because she is a lady and very rich and of the higher class. Anyone who was below her would put up with her behaviour because it was not his or her place in those days to accuse her of being impolite. Jane Austen grew up in this world where the rich people were almost the celebrities of the day. In our world famous people have the money, the expensive cars and clothes and a celebrity status, where the public would stop and look at them and always aspire to be like them. In Austens time it was very much the same but the lower classes and even middle were always looking up to the higher classes and admiring them. This is why people with the money could be as rude and stuck up to people as they wanted because in the end they were the ones with the power and the money to do what they wanted. Lady Catherines reason for visiting Elizabeth was not what the family had thought. Elizabeth expected a letter from Charlotte yet no letter was given. Instead Lady Catherine remarked upon a, prettyish kind of a little wilderness on one side of your lawn. Again she is not really being as polite as she could have been about the garden. From this point Elizabeth realised that she wanted to be alone. She had realised that Catherine was again being very rude and stuck up and so made no effort to talk to her. Lady Catherine begins with, your own heart, your own conscience, must tell you why I come. Elizabeth doesnt have any idea what she is talking about. Lady Catherine talks about her conscience, which is showing that Lizzy is to feel guilty about whatever she has been accused of. She tells Lizzy that rumours have reached her that her and Mr. Darcy were to be engaged and says though I know it must be a scandalous falsehood, Lady Catherine cannot comprehend this idea, to think that a middle class person such as Miss Bennet, who has no real connections, would even consider accepting an offer of this sort. Lady Catherine does not hold back on her true feelings about the subject and as Elizabeth has been brought up in the proper manner she has to respect her. Elizabeth soon becomes tired of her picking at everything that is wrong with her and her family and is not rude but stands up for herself. She asks Lady Catherine if the only reason they should not wed is because she wants him to marry her daughter, then what is there to stop her? She replies with honour, decorum, prudence, nay, interest, forbid it. This is the long list that she has against Lizzy. The social points she is trying to make is that in those days if a family were to have such a disgrace as Lydias elopement then no man should be interested in them, rich men such as Bingley and Darcy should marry same class or higher and that there were some very snooty people who would disagree with the association of certain families! They dont have a lot of land so are not as wealthy and high class.families like this always tried to marry higher up. Need to put in that Bennetts dont have a lot of land or money so lady Catherine looks down. Not too sure how to say this fits in with the rest of the book or how the chapter does? Bit stuck but will be done properly when handed in; in neat its a promise

Friday, September 20, 2019

Urinalysis of Four Urine Samples

Urinalysis of Four Urine Samples Urinalysis Practical Background: As you have learned, the urinary system performs many vital functions in the body including: Regulating blood volume and pressure by regulating water excretion, Regulating plasma ion/solute concentrations by adjusting urine composition, Assisting blood pH stabilisation, Removing nitrogenous waste, Conserving water and important nutrients and Assisting the liver in detoxifying poisons. Therefore, analysing a sample of urine from a person can provide important information on the health of that person. Urinalysis can reveal diseases such as diabetes mellitus, urinary tract infections and renal (kidney) infections such as glomeronephritis and kidney stones (renal calculi). A medical professional may perform a urinalysis for several reasons: As a general health check-up, Diagnosing metabolic or systemic diseases that affect renal function (heart failure will lead to decreased blood flow to the kidneys, pre-eclampsia during pregnancy will lead to increased protein in the urine), Diagnosis of endocrine disorders e.g. infertility (low levels of FSH and/or LH), Diagnosis of urinary system disease, Monitoring of glucose levels in patients with diabetes, Testing for pregnancy (hCG levels secreted by the embryo), Screening for drug use. Urinalysis is a technique involving physical, chemical and microscopic analyses of a sample of urine. Physical parameters: Normal urine is a clear yellow colour due to the presence of uribilin. Abnormal urine may be dark orange, red or brown and cloudy in appearance. This can be due to the presence of red and/or white blood cells or pigments and may indicate a urinary tract or renal infection or disease, liver or gall bladder disease. Normal urine has a specific gravity of between 1.002 – 1.028 (this is a measure of the number of particles/solutes in the urine, its concentration). A urine sample that has an elevated specific gravity can indicate dehydration, diarrhea/vomiting, glucosuria, inappropriate ADH secretion. A diminished specific gravity may indicate such diseases as renal failure or pyelonephritis. Chemical parameters: The chemical analysis of urine is routinely performed using an inexpensive and relatively accurate dipstick test (Uristix from Bayer or other brands). The test uses a reagent-coated plastic stick that is placed or dipped into the urine sample. The reagent areas change colour according to the presence of glucose and/or protein. (a) Figure 1. Colour chart (a) for determination of glucose and/or protein.   Ã‚   The glucose test on the dipstick is based on a double sequential enzyme reaction. One enzyme, glucose oxidase, catalyses the formation of gluconic acid and hydrogen peroxide from the oxidation of glucose (if present in the urine). A second enzyme, peroxidase, catalyses the reaction of hydrogen peroxide with a potassium iodide chromogen to oxidise the chromogen to colours ranging from green to brown. Normal urine has less than 0.1% glucose concentration. The protein test on the dipstick is based on the protein-error-of-indicators principle. At a constant pH, the development of any green colour is due to the presence of protein. Colours range from yellow for ‘negative’ through yellow-green and green to green-blue for ‘positive’ reactions. Normal urine has a protein concentration of less than 100  µg/ml. Although the dipstick test is semi-quantitative, significantly more accurate levels of glucose and protein can be determined by other means. In this practical you will use a BCA Assay (discussed later) to quantify the amount of protein present in a sample of urine. Urinalysis may also include assaying for levels of ketones (an indicator of diabetic ketosis, fasting or starvation), blood cells (indicating infection or kidney stones), bilirubin (liver or gall bladder disease), drugs and many other substances. Microscopic parameters: The urine sample can also be analysed by a microscope, often after staining to reveal any pathogens such as bacteria, urine crystals, cells and/or mucous. The presence of any of these may indicate infection or disease and further medical investigation will provide a thorough diagnosis. Aim: The aim of this practical is to perform glucose and protein urinalysis techniques on five samples of ‘urine’ provided by five ‘patients’ and use this information to provide an initial diagnosis for each patient. Part One: Using Dipsticks To Provide A Qualitative Measure of Protein And/Or Glucose. Materials: 5 samples of urine labelled A – E (these will be required for Parts One and Two), 5 Uristix dipsticks. Method: Perform a basic physical analysis of the urine samples noting the colour and cloudiness of each sample: Urine A Urine B Urine C Urine D Urine E Colour Cloudiness Immerse a dipstick into each of the samples, wait 60 seconds and record your results using the colour chart in Figure 1 to determine if the sample contains glucose and/or protein or neither substance: Urine A Urine B Urine C Urine D Urine E Glucose Protein Ketones Negative Negative Negative Negative Strongly positive Blood Negative Negative Trace Negative Negative Part Two: Using A Commercial BCA Assay To Provide A Quantitative Measure of Protein. Background: The BCA Protein Assay exploits the chemical reduction of Cu2+ to Cu1+ by protein in an alkaline medium with the selective colorimetric detection of the cuprous cation (Cu1+) by bicinchoninic acid (BCA). The first step is the chelation of copper with protein in an alkaline environment to form a blue coloured complex. In this reaction, known as the biuret reaction, peptides containing three or more amino acid residues form a coloured chelate complex with cupric ions in an alkaline environment containing sodium potassium tartrate. Single amino acids and dipeptides do not give the biuret reaction, but tripeptides and larger polypeptides or proteins will react to produce the light blue to violet complex that absorbs light at 540 nm. In the second step of the colour development reaction, BCA, a highly sensitive and selective colorimetric detection reagent reacts with the Cu1+ that was formed in step 1. The purple-coloured reaction product is formed by the chelation of two molecules of BCA with one Cu1+. The BCA/Cu complex is water-soluble and exhibits a strong linear absorbance at 562 nm with increasing protein concentrations. The rate of BCA colour formation is dependent on the incubation temperature, the types of protein present in the sample and the relative amounts of reactive amino acids contained in the proteins. Figure 2. Reaction diagram for the bicinchoninic acid (BCA) protein assay. Materials: The 2 samples of urine from Part One that were positive for protein, Protein stock standard (BSA, bovine serum albumin) at 1mg/ml, 0.9% Saline (diluent) BCA (bicinchoninic acid) Working Reagent (labelled BCA WR), 6 Tubes for dilutions for the standard curve, 96 Well microtitre plate, P100, P200 P1000 pipettes tips, Marker pen, 37ËÅ ¡C Incubator, Microtitre plate reader set to read at a wavelength of 562 nm. Method: Set up the dilutions for your standard curve, Label your tubes as 1,2,3,4,5 6, Prepare your standards according to the table below: Dilution tube # Volume of diluent ( µl) Volume of BSA or from tube # ( µl) Final BSA (protein) concentration ( µg/ml) 1 0  µl 300  µl BSA 1000 2 250  µl 250  µl bsa 500 3 250  µl 250  µl Tube 2 250 4 250  µl 250  µl Tube 3 125 5 800  µl 200  µl Tube 4 25 6 Blank 250  µl 0 0 Label your microtitre plate so that you know which wells hold your standards and which contain your samples (perform in triplicate), Pipette 25  µl of each standard (in triplicate) and sample (in triplicate) to each well, Add 200  µl of the Working Reagent to each standard or sample and shake for 30 seconds, Cover the plate and incubate at 37ËÅ ¡C for 30 minutes, Cool the plate to room temperature, Measure the absorbances at 562 nm on a microtitre plate reader, insert the average values in the table below: Dilution tube # Average absorbance at 562 nm (add 3 values divide by 3) Subtract blank (Tube 6) from value in previous column Final BSA (protein) concentration ( µg/ml) 1 1000 2 500 3 250 4 125 5 25 6 Blank 0 Sample 1 Sample 2 Prepare your standard curve: use the corrected absorbance readings for standards 1 – 6 (in column 3 in the previous table) and plot them against the amount of BSA in each tube, Once you have plotted your standard curve, you can determine the protein concentration in your samples, enter this value into the table above.   The patient scenarios are outlined below. You now need to match the urine samples with their corresponding patient scenarios and include justification for your decisions in your practical report: Patient Scenarios: Kidney Stones: Nida is a 17 year old student. She arrives at her GP feeling nauseous, feverish with acute pain in her lower back. She is also passing large amounts of blood in her urine. Glucose Drink: Thomas has just started a new job but is feeling quite stressed has lost weight. He arrives to see his GP but has had to skip lunch so drinks a litre of cola to maintain his energy levels. Diabetic: Jenny is studying for her A levels. Recently she has been losing weight although she is eating much more than usual is always hungry. Athlete: Dave is a professional athlete requires a blood urine test before competing in his next event. His test results are negative for drugs but are positive for another substance. Nephrotic syndrome: Keely is a 20 year old student. She has been feeling very unwell for some time with general fatigue, listlessness, weight loss puffiness around her eyes ankles. Her urine is very sparse very dark in colour

Thursday, September 19, 2019

Selena Quintanilla :: Music, Tejano Music

Barrera 2 Selena Quintanilla-Perez was an artist in the Tejano music industry that contributed to revolutionizing the style of music in the United States today. The Tejano music genre is originated from Texas but it may be called Tex-Mex because of its Mexican background. Selena absolutely loved her fans so she went to great lengths in order to keep her fans happy. (Angelfire 2) Her rise to stardom was also very successful thanks to the support and persistence from her father. She won a lot of awards and achieved amazing records in her musical career. The band that her family formed not only helped her find fame but it also helped her find love in a musician named Chris Perez.(Hispanic 2) Once she rose to stardom Selena was not corrupted by money. It appeared that her fame made her cherish her family a lot more and become less selfish by supporting charities. (Biography 1) The brink of her successful career was short lived due to a traumatic murder caused by the betrayal of Yolanda Saldivar. Selena was a Tejano artist that changed the style of music by uniting a clash of several cultures and therefore leaving a mark in history even after her death. (Texas 2) Fame never comes without a price and Selena paid that price by living a short, difficult childhood. While eight year old girls were outside having fun Selena was out singing at bars, weddings, fairs, and restaurants. She lived in an unstable household that eventually relied on the family band, â€Å"Selena y Los Dinos†, to eat and have a roof over their heads.

Wednesday, September 18, 2019

The Road Not Taken Analysis :: Free Essays

Line 1 In this line Frost introduces the elements of his primary metaphor, the diverging roads. Back to Poem Lines 2-3 Here the speaker expresses his regret at his human limitations, that he must make a choice. Yet, the choice is not easy, since "long I stood" before coming to a decision. Back to Poem Lines 4-5 He examines the path as best he can, but his vision is limited because the path bends and is covered over. These lines indicate that although the speaker would like to acquire more information, he is prevented from doing so because of the nature of his environment. Back to Poem Lines 6-8 In these lines, the speaker seems to indicate that the second path is a more attractive choice because no one has taken it lately. However, he seems to feel ambivalent, since he also describes the path as "just as fair" as the first rather than more fair. Back to Poem Lines 9-12 Although the poet breaks the stanza after line 10, the central idea continues into the third stanza, creating a structural link between these parts of the poem. Here, the speaker states that the paths are "really about the same." Neither path has been traveled lately. Although he’s searching for a clear logical reason to decide on one path over another, that reason is unavailable. Back to Poem Lines 13-15 The speaker makes his decision, trying to persuade himself that he will eventually satisfy his desire to travel both paths, but simultaneously admitting that such a hope is unrealistic. Notice the exclamation mark after line 13; such a punctuation mark conveys excitement, but that excitement is quickly undercut by his admission in the following lines. Back to Poem Lines 16-20 In this stanza, the tone clearly shifts. This is the only stanza which also begins with a new sentence, indicating a stronger break from the previous ideas.

Tuesday, September 17, 2019

The Consensus Perspective Essay -- Crime

Criminologists have long tried to fight crime and they have developed many theories along the way as tools to help them understand criminals. In the process of doing so, criminologist have realized that in order to really understand why criminals are criminals, they had to first understand the interrelationship between the law and society. A clear and thorough understanding of how they relatively connect with criminal behavior is necessary. Therefore, they then created three analytical perspectives which would help them tie the dots between social order and law, the consensus, the pluralist and the conflict perspectives. Each provides a significantly different view of society as relative to the law. However, while they all aim to the same exact purpose which is to help us understand crimes from a social viewpoint, the consensus perspective is more effective as it presents a more radical and logical view of how society interacts with the law. For instance, the consensus view focuses m ore on norms, unification, and equality. At the same time, it questions individuals ‘self-control as causes of crime. As Michalowski described it, most members of a society believe in the existence of core values (Schmalleger, 2012). The consensus view is about nothing but values, the different that are commonly known as right and wrong. The teaching of those values start at a very early stage of one’s life and we tend to adapt to them quite effectively. Most importantly, they become part of our lives to a point where we do not very much need a piece of paper to demonstrate it, we just grow to know that, for example, the killing of another person is wrong and respect for others is right. Those are the things that we know and believe and what makes it ... ...at it really is. It presents society as a united force respecting and following the norms as to every member can be satisfied. It is equal and common as to what is what and what to expect. It also projects that there probably would not be laws if it were not for the norms, as we, as a society agree on what is unacceptable and considered a violation. Finally, the consensus perspective sees violators of the norms as weak people with very low self-control. Bibliography Agnew, R. (2011). Toward a Unified Criminology: Integrating Assumptions about Crime, People and Society (New Perspectives in Crime, Deviance, and Law Series). New York: NYU Press. Luckenbill, E. H. (1992). Principles of Criminology (The Reynolds Series in Sociology). New York: Altamira Press. Schmalleger, F. (2012). Criminology Today: An Integrative Introduction. New Jersey: Prentice Hall. The Consensus Perspective Essay -- Crime Criminologists have long tried to fight crime and they have developed many theories along the way as tools to help them understand criminals. In the process of doing so, criminologist have realized that in order to really understand why criminals are criminals, they had to first understand the interrelationship between the law and society. A clear and thorough understanding of how they relatively connect with criminal behavior is necessary. Therefore, they then created three analytical perspectives which would help them tie the dots between social order and law, the consensus, the pluralist and the conflict perspectives. Each provides a significantly different view of society as relative to the law. However, while they all aim to the same exact purpose which is to help us understand crimes from a social viewpoint, the consensus perspective is more effective as it presents a more radical and logical view of how society interacts with the law. For instance, the consensus view focuses m ore on norms, unification, and equality. At the same time, it questions individuals ‘self-control as causes of crime. As Michalowski described it, most members of a society believe in the existence of core values (Schmalleger, 2012). The consensus view is about nothing but values, the different that are commonly known as right and wrong. The teaching of those values start at a very early stage of one’s life and we tend to adapt to them quite effectively. Most importantly, they become part of our lives to a point where we do not very much need a piece of paper to demonstrate it, we just grow to know that, for example, the killing of another person is wrong and respect for others is right. Those are the things that we know and believe and what makes it ... ...at it really is. It presents society as a united force respecting and following the norms as to every member can be satisfied. It is equal and common as to what is what and what to expect. It also projects that there probably would not be laws if it were not for the norms, as we, as a society agree on what is unacceptable and considered a violation. Finally, the consensus perspective sees violators of the norms as weak people with very low self-control. Bibliography Agnew, R. (2011). Toward a Unified Criminology: Integrating Assumptions about Crime, People and Society (New Perspectives in Crime, Deviance, and Law Series). New York: NYU Press. Luckenbill, E. H. (1992). Principles of Criminology (The Reynolds Series in Sociology). New York: Altamira Press. Schmalleger, F. (2012). Criminology Today: An Integrative Introduction. New Jersey: Prentice Hall.

Monday, September 16, 2019

How It Affects Economic Growth Essay

In my opinion, supporting and promoting IT investment is one of the best ways to promote economic growth and stability with minimal side effects such as inflation, and easily overcome hurdles like unequal income distribution. While I don’t think you can really influence people’s personal ownership of computers, I do believe that offering tax incentives for IT investment and development will increase overall GDP, lower unemployment, and ensure an economically stable future. First and foremost, investment towards information technology increases productivity, and makes workers more efficient in what they do. With more resources such as faster word processing, 3D Model Rendering, and instantaneous transfer of data over the internet, laborers in every facet of the economy benefit from technology and enjoy greater productivity as a result. This increase in productivity means more products and services are produced with less time invested, and this means that Gross Domestic Product can go up. Furthermore, GDP is often defined as a function of both Capital and Labor. It is widely acknowledged that GDP growth can be measured by K/L, or Capital divided by Labor. Clearly, then, if each worker is using a higher value of capital (here in the form of fancier computers etc), then GDP is sure to go up. The concern then becomes, â€Å"what about inflation?† Surely, if GDP goes up, inflation will follow, no? Not quite. The accompanying graph gives us a rough idea of why. This increased efficiency will shift the Philips curve inward, meaning that for every unemployment rate, there is less inflation. More IT investment will mean that we will require more service technicians, troubleshooters, software programmers, etc, and we will see unemployment go down. Also, with more children learning about IT, they will also be more likely to get jobs when they grow up. When unemployment goes down, though, we typically see that there are less available â€Å"desperate† workers, and thus workers will have more power to bargain collectively. They will get wage increases, which will be passed on to consumers in the form of higher prices on final goods and services. This is offset by increased efficiency, as it takes less worker hours to make those products and services. As the Philips curve below shows us, the decrease in unemployment WOULD cause higher inflation, but because of increased efficiency, this change in inflation is offset. It is important to note the short run and long run effects of tax incentives on both the macro and micro levels. Here is a graph to get us started: We know that in the short run Demand shifts out as IT becomes more and more necessary. Supply shifts out because manufacturing costs go down, and thus existing firms will produce more at every price. These reductions to cost shift MC and ATC down; we don’t’ know how much each of these shifts is, though. We don’t know what P2 is, but we know that costs go down, so there is abnormal short term profit, and we know that each firm is going to produce more. In the long run, more firms will enter (shifting supply out further) until each player in the market is operating at their lowest cost on the ATC curve, which is the point where long run profits are equal to 0. We know that long run market quantity is greater because there are more firms in the industry, and we know that each firm produces in the long run what it did before all the shifts. Each firm is producing more in the short run than in the long run. Assuming that the government offers tax incentives to BOTH SUPPLIERS AND BUYERS of IT, we can expect to see the same demand shifts and supply shifts as we did in the 90s, when demand shifted out and the cost to produce came down. The tax rebates to suppliers means a reduction of cost (same as in the last example) and the tax rebates to buyers will make the price they have to pay lower, which will increase demand. One of the few drawbacks to the subsequent increased IT spending, of course, is the negative effect on the environment, as computers become obsolete quickly and are usually just thrown out. In my opinion, the environmental effect is definitely a huge drawback to increased IT investment. I believe that the government should give further incentives to companies who donate old or â€Å"B-stock† products to schools (preferably those in bad areas) or charities when they buy new ones . Donating these slightly flawed or last-year-model computers to schools would be an investment in human capital, which would increase GDP in future generations, as children become more tech savvy and productive with computers. Since the government is reducing the cost of production with tax incentives, I think they could get away by contrasting these incentives with slightly stricter environmental regulations as far as waste goes. They should set requirements on the packaging (which is created solely to be thrown out) that comes with IT goods, and should give even more incentives to companies that collect and recycle re-usable components such as circuit boards, plastic cases, and semiconductors – all components that are not biodegradable and are a large part of the junk filling our nation’s landfills. Another set of short and long term effects you must consider is the effect of tax incentives on those already involved in the market: IT workers. Again, we have a graph to help us visualize these effects. For this discussion, because of inflation, we must assume that we are talking in terms of real dollars, and that these wage prices are adjusted for inflation. In the 1980’s (short run), as IT became more important to industry, we see the demand curve for IT work shift outward, causing an increase in price and quantity as more qualified people started doing IT. In the long run, more competitors enter and the number of CS majors doubles; supply shifts outward, but we’re not sure by how much. We know that real wages go back down, but we don’t know if they are above, at, or below the original prices. We just know that they are decreasing, and that the overall quantity is much higher. The last major concern would be the â€Å"Digital Divide† – the concept that low income families do not use computers and thus are isolated from their potential benefits. This â€Å"digital divide† essentially means that poorer families have less access to the computer and tech skills to compete in the modern job industry, such as word processing and online research. They also have less access to online educational resources, and thus have less human capital. This means they are less likely to rise out of poverty, and are at a disadvantage. Those fortunate enough to be able to afford computers & internet access will get more educated and richer, and those who are not fortunate enough get poorer. I personally am against racial discrimination in all forms, and I think targeting out minorities and saying â€Å"here, you need a computer† is wrong. I do, believe, however, that there should be some sort of program to give less fortunate children of all ethnicities the IT skills and access to computers that they will need to function in the modern labor market. This is where my idea of offering tax incentives to companies that donate â€Å"last year model† computers to charities or schools in bad neighborhoods could really benefit these people and help them accumulate human capital. I think that offering tax incentives to people who put computers in their home will be too difficult to manage, and I also think that in many cases, people without the means to get a good job (no technical background) will not be able to afford a computer either way – thus, it’s a vicious cycle. Additionally, I think people who can’t afford $40/mo for DSL are in this predicament because they don’t have technical skills, and thus, probably don’t value technology as much as they should. They probably still won’t be interested in broadband. I think the president’s broadband initiative should focus more on getting faster internet and more technical training into schools, so that the next generation, who still has the desire and patience to learn about computers, can do so at an early age. Overall, you can see that there is a long list of benefits, and a short list of easily overcome problems with increased investment. In fact, even the Fed benefits. Normally, increased investment would make the Fed have to increase interest rates to prevent inflation and â€Å"cool off† the economy. IT is unique, however, in that it also provides greater efficiency, thus shifting the curve as discussed earlier. I would argue that it makes the Fed’s job easier – it’s promotes economic growth and employment, without jeopardizing economic stability. All in all, I say that giving tax incentives to producers and suppliers of IT goods and services is a great plan!

Sunday, September 15, 2019

Explore and compare the characters, achievements and deaths of Lennie Small Essay

In this essay I will explore and compare the characters, achievements and deaths of Lennie Small, from John Steinbeck’s ‘Of Mice and Men’ and Bill Sikes from, Charles Dickens ‘Oliver Twist’. I have read both novels and enjoyed them immensely because of the wonderful characters, language and techniques used by the authors especially when describing the worlds they conjured within their novels. These two books also express perfectly the pioneering views of Dickens and Stienbeck; they both used their writings in an attempt to make their socialist views subtly heard by the masses. In the eras of Dickens and also Steinbeck, problems such as, racism, sexism, poverty and the class divide were simply accepted by society. These two authors saw the problems of their social structures, the discriminative attitudes of the people and wanted to make the public aware, being greatly frowned upon by some. Dickens and Steinbeck were soldiers of the same struggle and that is where the similarities between ‘Of Mice and Men’ and ‘Oliver Twist’ begin. Most of the characters in both novels represent the poverty that plagued both countries at the time the books were set, especially George and Lennie in ‘Of Mice and Men’; the epitome of poverty in the USA. Their lives are an endless trek around California constantly looking for work, scratching a buck or two a day from the back breaking work they do on the ranches. The poverty Oliver lives in (and that Dickens also experienced as a youth) is just the same, with a different back drop, which is why these novels relate so well to each other. Where these two stories really raise a lot of similarities, but at the same time a lot of paradoxes, are definitely the murder scenes and the deaths of the killers themselves. The characters and situations appear to be very alike, but once you read deeper you can see the differences that sneak through. Lennie Small is a very big, powerful, strong man; Steinbeck describes him as a bull. Sikes is also a large burley fellow, but where Sikes is pure evil, Lennie is childish, innocent and inhibited, a man who entirely relies on someone else to guide him, like a dog and master; their personalities are almost an antithesis. They are like this to bring out certain emotions in the reader to make us feel, hatred towards Sikes (and ultimately satisfaction when he dies), but sympathy, love and empathetic humour for Lennie. Their victims, on the other hand, are almost identical; Nancy is a prostitute and, in a way, so is Curley’s wife; she gives her body to Curley in exchange for marriage and money. We have to feel sorry for Curley’s wife when she when she confesses her sins to Lennie in the barn and the unfortunate way she has been mistreated and abused in the past. The sad thing is she is so naà ¯Ã‚ ¿Ã‚ ½ve that she doesn’t realise. She confesses that she doesn’t love or even like Curley: â€Å"I don’ like Curley. He ain’t a nice fella†¦Ã¢â‚¬  is exactly what she says to Lennie, something she has never told anyone. Nancy also repents before she dies and pleas with Bill to do so too: â€Å"†¦ let us both leave this dreadful place, and far apart lead better lives†¦ It is never too late to repent.† She even breathes a short prayer of mercy before she dies. In actual fact the whole reason Sikes kills Nancy is because she has been trying to do the lawful, honest thing and try to work her way out of this life of crime and sin she has lived in for so many years. We feel a lot more sympathy for Nancy when she dies because of this and for other reasons. To start with she is killed by a man contained with pure malice, hatred and evil, who is supposed to be her lover. Contrastingly Curley’s wife’s death is a complete accident or if anything, her fault. Also Dickens writes Nancy’s murder scene so graphically and violently it is almost impossible not to feel sorry for this woman: â€Å"†¦ Beat it twice upon her upturned face.† She must have died in agony and terror when Sikes killed her in cold, merciless blood. Nancy had to wait for her death in absolute terror for a minute or so, knowing she would be violently murdered, which must have seemed like an age, she even gets down on her knees and begs for mercy before she is savagely and callously slain. On the other hand Curley’s wife dies quickly and painlessly. There is a simple reason why this is. Dickens wants us to feel nothing, but pure, unadulterated hatred for Sikes when he kills Nancy, so when Sikes finally dies we feel justice is done. This is slightly because of Dickens’ audience, the Victorian public, being so religious and believing themselves to be so good hearted, would have demanded the death of Sikes and enjoyed the novel more without Sikes shadow hanging over the proceedings. Dickens being the man he was gives the people what they want. I prefer the way Steinbeck handles his murder scene purely because I think it is extremely clever. Steinbeck’s’ characterisation of these two characters has been leading up to this moment and it comes together perfectly. He intends us to feel sorry for Curley’s wife, but no hatred of any kind towards Lennie. Even though we have just heard of all the false promises she has been made in her life along with her failed ambitions, her belief they could still come true, all the times she has been sexually abused and the fact that she is still oblivious to all of this, we still can strongly empathise with Lennie. He is as innocent as the day he was born, a child trapped in a mans body. Lennie doesn’t have a scratch of malice in him and we could never feel anger toward a character we have come to love. After reading this scene I actually found myself almost as sorry and sympathetic towards Lennie as Curley’s wife, but not only Lennie, Candy and George too because I knew that any hopes of their long awaited dream had now been shattered. Finally in the two murder scenes to makes us feel complete hatred for Sikes and sympathy for Lennie the two authors both use similar metaphors to give the final impression that the two confessed and repented women are forgiven. With Nancy she is released from this world in the form of one of her hairs being cremated above the glowing embers and symbolically having her soul rise to Heaven. The scene after Curley’s wife is killed is heavenly enough, with the soft light of the mid-afternoon sun penetrating between the planks of the barn and the golden straw almost ceremoniously spread across the fallen maidens body, utter peace. A single dove, the messenger of God, flies in through the open barn door circles, almost giving the site its blessing, and exits with Curley’s wife’s soul on a journey to the heavens. Now I will move on to Lennie and Sikes’ deaths. In contrast to Nancy, when Sikes dies he falls straight to hell. His death is showered in chaos and fear twice that of what Nancy felt. It is a chase through the lowest and darkest place of London. A mad crowd of angry people screaming for Sikes’ blood, holding torches aloft like a crazed lynch mob. This ‘hue and cry’ of gentlemen, policemen, thieves and citizens of all kind all share a hatred and loathing of Sikes and what he has done. The way Dickens describes this scene is superb. When reading I could hear the shouts and screams of the crowd, feel the heat of the torches and feel Sikes’ fright: â€Å"†¦ a waving crowd in the outer darkness like a field of corn moved by an angry storm!† is probably one of the best pieces of description he uses and it really does make you feel the sense of chaos and vengeance that spurs on this ‘hue and cry. The satisfaction that it gives the reader when Sikes accidentally kills himself is enormous. In his efforts to escape he ties a rope around his waist and falls 40 feet as it moves to his neck and hangs him. Sikes dies in more agony than anyone else in either novel; not from pain, but fear. In the time he falls, his body experiences sensory overload; a panic and fear so great it is enough to kill a man on its own. He falls towards the crowd of flames and symbolically hell, the complete antithesis of the deaths of Nancy and Curley’s wife. Hanging would also have greatly contented the puritan population of Victorian England as hanging was the accepted capital punishment of the period, perfect for Sikes. To eradicate completely any emotion for Sikes his loyal dog also jumps for his master, smashing its head on the ground below. Any empathy we may have is transferred to Bullseye. This is probably the most dramatic of the entire novel. If one scene in ‘Of Mice and Men’ could match the pure drama and tension of Sikes’ death it would have to be the final chapter – Lennies death. The build up of tension in the scene is literal genius. When George produced Carlson’s’ Lugar I was on the edge of my seat right up until the end of the novel. Sikes’ death had to be quick to give a real sense for the excitement of the chase. Lennies death had to be draw out and milked for all it is worth, not solely for tension, but to give a character we have become so familiar with and very fond of, a memorable and proper send off. Thanks to George’s skill with words and his love for him, Lennie could not be more content when he dies. The last thing I wanted was for Lennie to die, but it is inevitable. I found myself sating ‘don’t do it George,’ but it is much better that he dies like this than face the men from the ranch. He must die; he cannot go on being tortured by what he has done. Lennie’s death shares some similarities to Curley’s wife’s; they both die quickly and painlessly and like Curley’s wife his soul is take to heaven. The gunshot rolling up the heavenly hills of Salinas makes you feel that Lennie has been released. To summarise, these to classic novels have many things in common, but also sharply contrast each other. It’s this that makes comparing the two so fascinating, as you new things they share and interesting differences every time you read them. It seems strange, but pleasing that two such comparable novels could come from different centuries, different, different countries, but share the same messages and morals.

Actions vs thoughts Essay

Thoughts†¦they are the basis for our creativity and are what separate us from other animals. Without thinking, we are just mindless zombies living for the sole purpose of surviving. We do not act without putting some thought into it. Some say that thinking without an action is pointless, because it will accomplish nothing in the real world . But, that is not true. In mathematics, we connect problems and solve them all in our heads, and we can apply those problems in the real world. We have to think ,so that we are able to process what is happening around us and apply it to our situation. Thinking is what leads to actions, so obviously thinking is more important than just an action. Although, in most religions, you have to show your devotion by using your actions. Which helps prove the quote â€Å"Actions speak louder than words.† But, the actions that are significant enough to be noticed are based on the thoughts that went into creating it. People tend to retain what they learned when it’s hands on. They learn by doing rather than thinking. They want to learn from their mistakes , so that they understand how to apply it and correct that mistake. Kinesthetic learners is the definition for people who learn better by doing rather than thinking. So, in some instances, thinking it through and being rational and precise is more important than doing. But in other instances, we thrive inexplicably by just going with the flow and allowing your actions to speak louder than words to become more important than them.

Saturday, September 14, 2019

Is life cycle Essay

The life cycle of information systems impact the organization in several ways and can be summed as follows: †¢ System investigation: The primary analysis of the system is essential for enveloping all the business data and information requirements to map all processes in the organization (Hoffer, 2002). It is done so that no data is left out and there is 100% coverage of the business requirements. The requirements of this stage demand enough expertise and skill to effectively understand and capitalize on information so that information is captured to its full swing. †¢ Systems analysis and Design: Once all the requirements are collected successfully they are analyzed to their importance and framed into defined design models such as DFD, E-R diagram and others so that their modeling is successfully transformed into a working system (Navathe, 2004). The entire design reflects the working of the organizational processes and their penetrations with external forces. The capabilities of this stage demands business modeling methods and strategies for developing a suitable data flow diagram to correctly figure out the process. †¢ Systems coding: This is the actual step where the business requirements are actually implemented and taken care to be given a representation. The impact of this stage would result in greater understanding of the business methods and good communication skills with the client. This stage creates an impact to make a difference to code the system to exact requirements mapped in the planning stages. †¢ Systems implementation: Successful implementation of the system is essential for the system to facilitate working and for the users to take full advantage of the system. The impact of this stage is quite large as improper implementation strategies may affect the working of the organization and processing capabilities. The above four stages impact the working of the organization as they are directly related to create a system to map the organizational processes. References Hoffer (2002). Modern systems analysis and Design (pp 241-263). Singapore: Pearson Education. Navathe, Elmasri (2004). Fundamentals of Database systems (pp 49-70). Singapore: Pearson Education.

Friday, September 13, 2019

Globalization and Business IT Research Paper Example | Topics and Well Written Essays - 3000 words

Globalization and Business IT - Research Paper Example al., 2008). Information technology (IT) and the globalisation of business have made the global supply chain very efficient and contributed to large profits in the business. Both IT and globalisation are aspects of modernisation and growth. IT sector is one of the most booming sectors and the globalisation focuses on the overall development of a country, market, sector and industry among others. Fedex, as a company, strongly believes in globalisation and therefore manages to provide its services globally. The company operates a large range of branded companies which come under the main brand Fedex, and all these companies serve logistics services. With the incorporation of IT, FedEx has been able to leverage superior globalised service by entailing technologically upgraded features in its global operations such as wireless technology and shipping along with tracking system (Network World Fusion, 2002; Cisco Systems, 1999; Butcher & et. al., 2008). Title IT and globalisation’s c ontribution to business for improving the supply chain cycle in a global scale: An illustration of FedEx Research Question For completing the proposed research, it is required to find out the contributions that are made by IT and globalisation in business and the process through which IT and globalisation has made the overall supply chain cycle more effective and contributed to greater profits in the business of FedEx. Therefore, for the completion of the proposed research study, the main question that will be addressed upon will be: How did IT and globalisation managed to improve the overall supply chain process in a global scale which resulted in improved business and profits for FedEx? Specific Project Objectives The... This essay approves that a proper understanding of globalisation and its positive effects in the context of supply chain should be understood and found. Apart from this, it should also be analysed that whether FedEx has already achieved a sustainable amount of growth or not. Whether the company has reached the saturation level or not? If yes, then are there any future scope of development for the company or does the company has any kind of future expansion plans. It is also required to be studied about the competitor companies of FedEx who are delivering similar services like the company to its customers. This report makes a conclusion that IT and globalisation are indeed very important factors contributing to the growth of business and it has made many contributions in changing the supply chain cycle. FedEx prioritises upon the concept of supply chain in a very prospective manner. However, there are few factors that require certain amount of understanding. The aim of this proposal has been to follow a proper research methodology which includes all the basic techniques of research and analysis for obtaining certain conclusion regarding the future plans, present operations, competitors and market standing of the company. In order to complete this proposed research, a questionnaire has been prepared which will be filled by the actual respondents/employees of FedEx and informal interviews will also be conducted in the company wherein the respondents will be the interviewee. These procedures will help in successful completion of the research by providing a clear picture of the operations in the company as well as the supply chain process that is currently being followed by the company and the different supply chain processes that the company may follow in the future.

Thursday, September 12, 2019

Quality of education in post-conflict in Rwanda and post-disasters in Essay

Quality of education in post-conflict in Rwanda and post-disasters in Pakistan - Essay Example Education can spare and support lives, offering physical, cognitive and psychosocial security when conveyed in protected, nonpartisan spaces. Education restores routine and gives individuals trust for the future; it can likewise serve as a channel both for meeting other essential compassionate needs and conveying basic messages that advance security and prosperity. During conflicts and catastrophes, education systems, students and personnel suffer the effects of the conflicts and catastrophes and forced displacement. Some of these effects include, loss of life, loss of property and loved ones, loss of educational opportunities, and mass rape and other sexual violence which is as a result of alteration of the school programs. Conflicts and catastrophes intensify inequality, disrupts the whole society. This can have severe psychological effects particular to the children who are in school (Schweisfurth, 2006). However, not having enough education worsens security and deepens poverty in a country. The presence of unequal education opportunities fuels a sense of injustice and grievances. Education of terrible quality can be exceedingly divisive, especially if choices about educational module content, course books or dialect of guideline prohibit or permit denunciation of some social gatherings, and if education strengthens messages that savagery i s a worthy answer to individual, social or political issues. Education has vast value for its own sake. This means that all young people and children, including those that have been affected by conflict and catastrophes have the right to receive a quality education. Nevertheless, education is needed in emergency setting to prepare the society for ultimate post-disaster and post-conflict reconstruction and social-economic development (Jones, 2006). Balanced development with economic development obliges that young people of all social, ethnic, religious and

Wednesday, September 11, 2019

Human resource management practice A substitute for trade unions Dissertation

Human resource management practice A substitute for trade unions - Dissertation Example Introduction Human resource management is a complete philosophy suggesting management of all personnel related issues in the light of vision of the organization and integrated with the organization’s strategy and policy (Pieper 1990). Traditionally, staff management is mainly targeted on tasks such as staffing, work design and rewarding however now the concept has been broadened to include in it personnel development and strategy specific actions. With this broad change where we talk about realizing the real potential of people and managing them in a way that they produce efficient results (Venter & Van der Waldt 2007) is it suitable to say that modern human resource management practice has substituted trade unions which were common a few years back to make the voice of laborers heard and acted. This research study, therefore, seeks to explore if human resource management practice has substituted trade unions or not. 1.1 Project Aims and Objectives As mentioned above research question guiding this research study asks has contemporary human resource management practice substituted trade unions. Having developed this research question, this research study seeks to attain following aims and objectives. To explore the role of modern human resource management in personnel management and development. To critically evaluate the role of trade unions in modern human resource management practice. To identify factors contributing to decline in trade unions if it is not modern HRM practices. 1.2 Project Approach This research study is primarily focused on secondary data and hence is categorized as desk research; Armstrong (2006, p. 53) defined desk research as â€Å"the assembly, collation and analysis of marketing information which is...Truss et al (1997) explained that hard HRM focuses attention on theory X whereas soft HRM focuses on theory Y. Truss et al (1997) examined that due to wide differences in these two approaches is it possible for an organization to u se both these models in integration; from their research they found that no organizations clearly follows any one of these models and though organizations focuses on commitment and conceptually targets to treat employees as humans (soft HRM concept) in reality where policies and strategic control is in action it is practically hard to stick to soft HRM and hence hard RM elements also come into action (Truss et al 1997). This study also looks into soft and hard HRM concepts and tries to relate it to the need of trade unions and which of the HRM versions may result in increase or decline in the number of trade unions. 2.4 Trade Unions and their Purpose Deb (2009) defined trade union as a representative body where employees are at the receiving end. Shmoop (2010, p. 1) defined labor union as â€Å"an organization established by and for workers to pursue collective workplace goals, benefits, work rules and power†.

Tuesday, September 10, 2019

Freedom of press Assignment Example | Topics and Well Written Essays - 500 words

Freedom of press - Assignment Example However, internet journalism suffers from a lack of structure that often results in ethical breaches and creation of content that is not informative or reliable. While the potential for internet as a tool for mass information is great; its biggest advantage is also its greatest weakness. With so many players in the information sector and a emphasis on being the first one to break a news; there is no check on the quality of the material is produced and distributed, no benchmarks in place and no enforcement of journalistic standards. â€Å"It is clear that digital journalism can allow for greater commitment to editorial standards. From better linking to primary sources of information, to greater commitment to transparency, there has never been an age more able to incorporate open, high-quality journalism† (Riordan). The problem is that online with so much free content available, websites are in a desperate race to get the most viewers and increase ad revenues. There is a significant occurrence of â€Å"Click-bait† in internet media outlets, where readers are enticed by sensational, often exaggerated headlines into going to a website link for a news article which may be unrelated to the exact heading. The practice is done to increase the number of users for a certain website and it compromises the integrity of the news. The worse scenarios are in which the news itself is falsified to create reader interest, one innocent example of this phenomena are related to the launch of the iphone 6 which was soon accompanied by news stories about the phone bending under slight pressure or people falling to pranks about charging the phone. These news stories were debunked within a few days but created a significant interest among fans and critics of the phone alike. More seriously, in the Gaza-Isreal conflict a lot of the news that was passed around on social media was

Monday, September 9, 2019

MGM330-0704A-04 Business Decision-Making - Phase 1 DB Essay

MGM330-0704A-04 Business Decision-Making - Phase 1 DB - Essay Example This discussion describes the different data collection methods, the issues associated with them and the situations each method is more suitable for. Social studies is a field which utilizes a lot of statistics in its studies. In order for some of the data to be unbiased a common method utilized to study human behavior and obtain qualitative or quantitative data is observation. Observation is a controversial data collecting method when utilized without people knowing there are being watched in scenarios such as in a public place. Interviews are very effective data collection methods for statistics involving in fields such as human resources. The data collected is easy and cheap to acquire, but at times sophisticated statistical models involving techniques such as hypothesis tests or multiple regression models are required (McClave & Benson & Sincich, 2001). A survey is a simple to implement data collection method. It can be utilize to obtain data extremely fast and allows the opportunity to be performed electronically because of its simplicity with the assistance of the internet. In the case of Piggy banking this company could utilize this data collection method in a lot of applications at the bank. A bank can create surveys and place them anywhere in the branch for customers to answer while they are waiting for a finance official to provide them with service at the branch. Another method that is commonly used to obtain data that can be utilized in statistical work is research. Research is an effective method to obtain secondary data. Secondary data is obtained utilizing readily available sources, in other words the data is collected by someone else and utilized by the researcher for a statistical study (Fao). This data can be collected extremely fast. On the other primary data which is collected by the researcher himself/herself is a very time consuming task. At times secondary data is not available and the only way to

Sunday, September 8, 2019

Ford and the World Automobile Industry Essay Example | Topics and Well Written Essays - 2250 words

Ford and the World Automobile Industry - Essay Example This paper illustrates that in order to respond to the competitive threat, Ford’s Chief Financial Officer had emphasized upon the longer term financial outlook. To this end Ford’s management had implemented plant closures which had resulted in reductions in fixed cost. Additionally the company had made an early switch to smaller, more fuel-efficient cars and sold loss-making Jaguar, Aston Martin and Land Rover subsidiaries. As a result of these initiatives, Ford had improved its financial and operating performance. However if the company were to maintain its performance, then it would have to focus upon the combined forces of technology and environmental forces that were changing the industry structure and formulate strategies accordingly. Competition in the world auto industry The industry was facing rising competitive pressures due to a variety of factors. Experts had expected the industry to consolidate from the demand pressures that had resulted from the financial c risis of 2009. Instead the outcome had been one of worsening the problem of excess capacity as national governments provided financial assistance to support those companies which were suffering from the downward trend in demand. Therefore the weaker competitors had not been weeded out. Instead they increased their production, thus worsening the problem of excess capacity. This was the most important factor which contributed to the rising competitive pressures. The world auto industry was far from being static as demand shifted from mature industrial nations to the growing markets of Asia, Eastern Europe and Latin America. These dynamics had forced the automakers to implement strategies aimed at seeking new markets as additional sources of demand. Between 1990 and 2008, the five biggest automakers were GM, Toyota, Ford, Daimler-Chrysler and Volkswagen. The evolution of market demand had been affected by the combined forces of technology and environmental concerns. For this reason For d planned to make the switch to all-electric commercial vans and automobiles. This change in strategy had also been necessary because of the shift of market opportunities to the growing markets of Asia, Eastern Europe and Latin America. As a result the automobile producers were changing strategic focus to emphasize upon the newly industrializing countries as new sources of market opportunities. Driven by the emerging markets in BRIC countries and in the newly industrializing countries such as Korea, Thailand, Malaysia, Turkey and Argentina, the supply of cars and trucks continued to grow. However new product development costs limited automakers abilities to differentiate products. For this reason there was little differentiation between manufacturers. The industry’s key issue was excess capacity. As noted in the case, consultants at PwC had estimated that supply exceeded demand by 31 million units per year. The problem had been exacerbated by government intervention which has kept inefficient companies afloat. Applying Porter’s five forces analysis, the conclusion to draw is that the threat of new entrants would be low since supply exceeds demand. The threat of substitute products came from electric cars which would offer opportunities for new entrants. The transition to electric cars would enable companies with expertise in electrical engineering to enter the industry, thus intensifying competition. Public transportation also offered a substitute. The threat of competitive rivalry in the present state of the industry was considerable since supply exceeded demand.

Saturday, September 7, 2019

The Relationship Between Health, Healing, and Religion Term Paper

The Relationship Between Health, Healing, and Religion - Term Paper Example Different religions utilize different ideas about the healing. Some utilize the spiritual activities while some utilize the scientific approach and give medicines to heal a sick person. The medicine might come from the plant source or might be a modern medicine. The modern scientific community has taking interest in all the healing techniques that are utilized from the religious point of view and some of the religious activities considering the health and healing got importance due to the positivism towards the society and religion. In general, illness is the phase of a body or mind where it is unable to work in its capacity or body or mind is unable to perform that it has the capacity of. However, different religions views illness differently. In the Voodoo religion, the believers have believed that an illness is caused due to the evil or bad sprits or sometimes sprits of the family members. Voodoo has concepts that â€Å"lwa† are the sprits that make an interaction with the people and are able to cause bad thing to the people. In the Kung religion, illness is caused by the dead Kung, the dead ancestor of a person or sometimes gods penetrate the illness into the person (Kingsley 41). In this way, in this religion it is very important to cure and heal the sick to try best to make the person healthy. Shaman has also the similar conditions that consider illness a spiritual deal of the person. In the shamanism, people believe that there is an invisible world around us and invisible creatures are present around us that are sprits. The sprits are able to put illness in a person. Yoga involves the practices that are capable of making the disease away from the practitioner. The practitioners have the faith that certain forces that block the life can cause illness. How is it best addressed? In different religions the illness is expressed in different forms and sometimes it referred to as the spiritual illness. In the religion ‘Kung’ people give spec ial important to the sick because they believe that if the person dies of illness (Kingsley 42), he will spread the illness or give it to the other person. In the Voodoo, illness is paid a significant attention and 60% of the activity in the religion is to heal the person. In the similar way the yoga also addresses the illness in a proper manner and to remove it from the person’s body and soul special attention is required. Yoga is all about the methods that increase the blood flow in the body, increase the brain function and make the body flexible and healthy. The practices utilized in the yoga can help maintain the blood pressure and reduce the cholesterol that helps maintain the health of the heart and the lungs. What kind of healer is needed? In almost all the religion, some of the persons of the society work significantly to preach and heal the persons like the priests, which make give their lives to the religion to protect and preach the religion and make people underst and what their religion is. In the similar way, in all the religion people consider then sacred and they are the person who work to heal the persons. In Voodoo, the priesthood presents both is man and women and these persons heal the ill persons with some rituals, herbal medicines and now a day the scientific medicines. Houngan is the word for the male priest and Mambo is the name of the female priest. Similarly, a healer is required in the Kung to make the illness away from the people and he can be able to fight with the gods to pull the illness away from the person, in this way, a healer should be strong both mentally and physical. In the similar way, in Curandero’s healing mechanism, saints play the role of the healer. In